About Tasigna
Tasigna Safety and Tolerability
Tasigna is generally well tolerated and has demonstrated a low incidence of cross-intolerance with Glivec (imatinib mesylate). Tasigna also was associated with a low rate of Grade 3/4 nonhematologic AEs, including low AEs related to fluid retention.
Most nonhematologic AEs were mild to moderate in severity.
- The most common AEs in the chronic phase were rash, pruritus, nausea, headache, and fatigue.
Tasigna was associated with a low incidence of AEs related to fluid retention
- Low incidence (<1%) of Grade 3/4 pleural or pericardial effusions
Tasigna has a negligible incidence of cross-intolerance with Glivec

The most common hematologic AEs (Grade 3/4) were neutropenia and thrombocytopenia.

AEs are measured regardless of relation to Tasigna
Source:
Nilotinib Summary of Clinical Safety: 120-Day Safety Update. Novartis Pharmaceuticals: East Hanover, NJ; 2007.
- Prescribing Tasigna
- Tasigna Efficacy
- Tasigna Safety and Tolerability
- European Summary of Product Characteristics
- Tasigna Mechanism of Action
- How to Dose


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